Gene entry
LAMA2
laminin subunit alpha 2
- Chromosome
- 6
- Cytoband
- 6q22.33
- Variants (rsID)
- 167
LAMA2 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 6 (region 6q22.33). Its official name is “laminin subunit alpha 2”. The reference table lists 167 variants (rsID) for this gene.
Clinically classified variants
63 reference-table entries with clinical significance.
- rs1049473Benignsingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency
- rs111381107Benignsingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs111695726Benignsingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs117781224Benignsingle nucleotide variantLAMA2-related muscular dystrophy|Congenital muscular dystrophy due to partial LAMA2 deficiency
- rs11967042Benignsingle nucleotide variant
- rs17057158Benignsingle nucleotide variantMerosin deficient congenital muscular dystrophy|LAMA2-related muscular dystrophy
- rs17741922Benignsingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs2229848Benignsingle nucleotide variantMerosin deficient congenital muscular dystrophy|LAMA2-related muscular dystrophy
- rs2306942Benignsingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|Merosin deficient congenital muscular dystrophy|LAMA2-related muscular dystrophy
- rs34367843Benignsingle nucleotide variantMerosin deficient congenital muscular dystrophy|LAMA2-related muscular dystrophy|Congenital muscular dystrophy due to partial LAMA2 deficiency
- rs35065563Benignsingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy|Intellectual disability
- rs35579821Benignsingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs35879899Benignsingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs36044314Benignsingle nucleotide variantLAMA2-related muscular dystrophy|Congenital muscular dystrophy due to partial LAMA2 deficiency
- rs3749878Benignsingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|Merosin deficient congenital muscular dystrophy|LAMA2-related muscular dystrophy|Muscular dystrophy, limb-girdle, autosomal recessive 23
- rs61749497Benignsingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs77113162Benignsingle nucleotide variantLAMA2-related muscular dystrophy
- rs79374915Benignsingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs112388307Conflicting interpretationssingle nucleotide variantLAMA2-related muscular dystrophy
- rs115488979Conflicting interpretationssingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs115650537Conflicting interpretationssingle nucleotide variantLAMA2-related muscular dystrophy|Congenital muscular dystrophy due to partial LAMA2 deficiency
- rs117422805Conflicting interpretationssingle nucleotide variantMerosin deficient congenital muscular dystrophy|LAMA2-related muscular dystrophy|Congenital muscular dystrophy due to partial LAMA2 deficiency|Intellectual disability
- rs117884199Conflicting interpretationssingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs118147866Conflicting interpretationssingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs121913573Conflicting interpretationssingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs121913574Conflicting interpretationssingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs140483001Conflicting interpretationssingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs141521127Conflicting interpretationssingle nucleotide variantLAMA2-related muscular dystrophy|Congenital muscular dystrophy due to partial LAMA2 deficiency
- rs142083777Conflicting interpretationssingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs142164767Conflicting interpretationssingle nucleotide variantLAMA2-related muscular dystrophy|Congenital muscular dystrophy due to partial LAMA2 deficiency
- rs142451929Conflicting interpretationssingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs142671449Conflicting interpretationssingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs143680577Conflicting interpretationssingle nucleotide variantMerosin deficient congenital muscular dystrophy|LAMA2-related muscular dystrophy
- rs144860334Conflicting interpretationssingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|Merosin deficient congenital muscular dystrophy|LAMA2-related muscular dystrophy
- rs147077184Conflicting interpretationssingle nucleotide variantMerosin deficient congenital muscular dystrophy|Muscular dystrophy, limb-girdle, autosomal recessive 23|LAMA2-related muscular dystrophy|Congenital muscular dystrophy due to partial LAMA2 deficiency
- rs149347601Conflicting interpretationssingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs149753273Conflicting interpretationssingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs150644209Conflicting interpretationssingle nucleotide variantLAMA2-related muscular dystrophy
- rs191899712Conflicting interpretationssingle nucleotide variantLAMA2-related muscular dystrophy|Merosin deficient congenital muscular dystrophy
- rs192317605Conflicting interpretationssingle nucleotide variantLAMA2-related muscular dystrophy|Merosin deficient congenital muscular dystrophy|Congenital muscular dystrophy due to partial LAMA2 deficiency|Muscular dystrophy, limb-girdle, autosomal recessive 23
- rs200646230Conflicting interpretationssingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs200796753Conflicting interpretationssingle nucleotide variantLAMA2-related muscular dystrophy|Congenital muscular dystrophy due to partial LAMA2 deficiency
- rs201375881Conflicting interpretationssingle nucleotide variantMerosin deficient congenital muscular dystrophy|LAMA2-related muscular dystrophy|Congenital muscular dystrophy due to partial LAMA2 deficiency|Muscular dystrophy, limb-girdle, autosomal recessive 23|Merosin deficient congenital muscular dystrophy
- rs369558532Conflicting interpretationssingle nucleotide variantLAMA2-related muscular dystrophy
- rs41285286Conflicting interpretationssingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs56035053Conflicting interpretationssingle nucleotide variantMerosin deficient congenital muscular dystrophy|LAMA2-related muscular dystrophy|Congenital muscular dystrophy due to partial LAMA2 deficiency|Intellectual disability
- rs56209257Conflicting interpretationssingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|LAMA2-related muscular dystrophy
- rs62421010Conflicting interpretationssingle nucleotide variantLAMA2-related muscular dystrophy|Congenital muscular dystrophy due to partial LAMA2 deficiency
- rs78880369Conflicting interpretationssingle nucleotide variantLAMA2-related muscular dystrophy|Congenital muscular dystrophy due to partial LAMA2 deficiency
- rs117096733Likely benignsingle nucleotide variant
- rs138018456Likely benignsingle nucleotide variantLAMA2-related muscular dystrophy
- rs121913569Pathogenicsingle nucleotide variantMerosin deficient congenital muscular dystrophy|LAMA2-related muscular dystrophy
- rs121913572Pathogenicsingle nucleotide variantMerosin deficient congenital muscular dystrophy|Merosin deficient congenital muscular dystrophy|Muscular dystrophy, limb-girdle, autosomal recessive 23|LAMA2-related muscular dystrophy|Congenital Muscular Dystrophy, LAMA2-related|Muscular dystrophy, limb-girdle, autosomal recessive 23
- rs121913576Pathogenicsingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency|Merosin deficient congenital muscular dystrophy|LAMA2-related muscular dystrophy
- rs186538779Pathogenicsingle nucleotide variantMerosin deficient congenital muscular dystrophy|LAMA2-related muscular dystrophy
- rs201632009Pathogenicsingle nucleotide variantMerosin deficient congenital muscular dystrophy
- rs794727594PathogenicDeletionMerosin deficient congenital muscular dystrophy|LAMA2-related muscular dystrophy
- rs9492297Pathogenicsingle nucleotide variant
- rs141000358Uncertain significancesingle nucleotide variantLAMA2-related muscular dystrophy
- rs143674727Uncertain significancesingle nucleotide variantLAMA2-related muscular dystrophy
- rs182958473Uncertain significancesingle nucleotide variantCongenital muscular dystrophy due to partial LAMA2 deficiency
- rs189360899Uncertain significancesingle nucleotide variantLAMA2-related muscular dystrophy|Congenital muscular dystrophy due to partial LAMA2 deficiency
- rs201177178Uncertain significancesingle nucleotide variantMerosin deficient congenital muscular dystrophy|LAMA2-related muscular dystrophy
Other listed variants
- rs265327
- rs265371
- rs265372
- rs265379
- rs265401
- rs737515
- rs1015845
- rs1027200
- rs1387918
- rs2297740
- rs2437090
- rs2437092
- rs2437095
- rs2451686
- rs2571574
- rs2571584
- rs2876041
- rs4144419
- rs4257879
- rs4273713
- rs4285345
- rs4397244
- rs4897285
- rs4897296
- rs6899448
- rs6905196
- rs6939307
- rs7356971
- rs7356972
- rs7453910
- rs7751571
- rs7751685
- rs7766548
- rs9321156
- rs9321159
- rs9385488
- rs9388686
- rs9482967
- rs9492234
- rs9492323
- rs10457513
- rs10499144
- rs10499146
- rs10499154
- rs12190465
- rs12193446
- rs12205363
- rs12211745
- rs12213754
- rs13193413
- rs13204236
- rs17056875
- rs17056876
- rs17056914
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.