Gene entry
IQSEC2
IQ motif and Sec7 domain ArfGEF 2
- Chromosome
- X
- Cytoband
- Xp11.22
- Variants (rsID)
- 34
IQSEC2 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome X (region Xp11.22). Its official name is “IQ motif and Sec7 domain ArfGEF 2”. The reference table lists 34 variants (rsID) for this gene.
Clinically classified variants
6 reference-table entries with clinical significance.
- rs147706810Conflicting interpretationssingle nucleotide variantIntellectual disability, X-linked 1
- rs267607186Conflicting interpretationssingle nucleotide variantIntellectual disability, X-linked 1|Intellectual disability
- rs371450118Conflicting interpretationssingle nucleotide variantHistory of neurodevelopmental disorder|Intellectual disability, X-linked 1
- rs781805662Conflicting interpretationssingle nucleotide variantIntellectual disability, X-linked 1
- rs797045629Conflicting interpretationssingle nucleotide variantIntellectual disability, X-linked 1
- rs886041481PathogenicDeletionSevere intellectual deficiency|Intellectual disability, X-linked 1|Inborn genetic diseases
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.