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Gene entry

IDH2

isocitrate dehydrogenase (NADP(+)) 2

Chromosome
15
Cytoband
15q26.1
Variants (rsID)
10

IDH2 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 15 (region 15q26.1). Its official name is “isocitrate dehydrogenase (NADP(+)) 2”. The reference table lists 10 variants (rsID) for this gene.

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Clinically classified variants

4 reference-table entries with clinical significance.

  • rs118101777Benignsingle nucleotide variantD-2-hydroxyglutaric aciduria 2
  • rs61737003Benignsingle nucleotide variantD-2-hydroxyglutaric aciduria 2
  • rs142816010Conflicting interpretationssingle nucleotide variantD-2-hydroxyglutaric aciduria 2
  • rs121913502Pathogenicsingle nucleotide variantD-2-hydroxyglutaric aciduria 2|Acute myeloid leukemia|Neoplasm of the large intestine|Squamous cell carcinoma of the head and neck|Myelodysplastic syndrome|Multiple myeloma

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.