Gene entry
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
- Chromosome
- 5
- Cytoband
- 5q13.3
- Variants (rsID)
- 20
HMGCR is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 5 (region 5q13.3). Its official name is “3-hydroxy-3-methylglutaryl-CoA reductase”. The reference table lists 20 variants (rsID) for this gene.
Clinically classified variants
2 reference-table entries with clinical significance.
- rs12654264Associationsingle nucleotide variantLow density lipoprotein cholesterol level quantitative trait locus 3
- rs17238540Othersingle nucleotide variantStroke, Ischemic|Coronary Heart Disease 1|Type 2 Diabetes Mellitus|Diabetes Mellitus|Myopathy
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.