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Gene entry

GRN

granulin precursor

Chromosome
17
Cytoband
17q21.31
Variants (rsID)
4

GRN is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 17 (region 17q21.31). Its official name is “granulin precursor”. The reference table lists 4 variants (rsID) for this gene.

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Clinically classified variants

2 reference-table entries with clinical significance.

  • rs25646Benignsingle nucleotide variantGrn-related frontotemporal lobar degeneration with Tdp43 inclusions|Seizure|Neuronal ceroid lipofuscinosis 11|Grn-related frontotemporal lobar degeneration with Tdp43 inclusions
  • rs63751294Pathogenicsingle nucleotide variantGrn-related frontotemporal lobar degeneration with Tdp43 inclusions|Grn-related frontotemporal lobar degeneration with Tdp43 inclusions|Neuronal ceroid lipofuscinosis 11

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.