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Gene entry

FREM2

FRAS1 related extracellular matrix 2

Chromosome
13
Cytoband
13q13.3
Variants (rsID)
71

FREM2 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 13 (region 13q13.3). Its official name is “FRAS1 related extracellular matrix 2”. The reference table lists 71 variants (rsID) for this gene.

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Clinically classified variants

16 reference-table entries with clinical significance.

  • rs116653247Benignsingle nucleotide variantFraser syndrome 2
  • rs116742938Benignsingle nucleotide variantFraser syndrome 2
  • rs141718695Benignsingle nucleotide variantFraser syndrome 2
  • rs143044921Benignsingle nucleotide variantFraser syndrome 2|Congenital diaphragmatic hernia|Congenital anomaly of kidney and urinary tract
  • rs2027770Benignsingle nucleotide variantFraser syndrome 2
  • rs61997174Benignsingle nucleotide variantFraser syndrome 2
  • rs74781600Benignsingle nucleotide variantFraser syndrome 2
  • rs79048205Benignsingle nucleotide variantFraser syndrome 2
  • rs9532292Benignsingle nucleotide variantFraser syndrome 2|Isolated cryptophthalmia
  • rs9603463Benignsingle nucleotide variantFraser syndrome 2
  • rs184635412Conflicting interpretationssingle nucleotide variantFraser syndrome 2|Microcephaly
  • rs201457616Conflicting interpretationssingle nucleotide variantFraser syndrome 2|Microcephaly
  • rs41292753Conflicting interpretationssingle nucleotide variantFraser syndrome 2
  • rs114341997Likely benignsingle nucleotide variantFraser syndrome 2
  • rs121434355Pathogenicsingle nucleotide variantFraser syndrome 2
  • rs114524483Uncertain significancesingle nucleotide variantFraser syndrome 2

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.