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Gene entry

FREM1

FRAS1 related extracellular matrix 1

Chromosome
9
Cytoband
9p22.3
Variants (rsID)
84

FREM1 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 9 (region 9p22.3). Its official name is “FRAS1 related extracellular matrix 1”. The reference table lists 84 variants (rsID) for this gene.

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Clinically classified variants

13 reference-table entries with clinical significance.

  • rs10961689Benignsingle nucleotide variantOculotrichoanal syndrome
  • rs117881664Benignsingle nucleotide variantOculotrichoanal syndrome
  • rs1353223Benignsingle nucleotide variantOculotrichoanal syndrome
  • rs200064797Benignsingle nucleotide variantOculotrichoanal syndrome
  • rs41265310Benignsingle nucleotide variantOculotrichoanal syndrome
  • rs61732355Benignsingle nucleotide variantOculotrichoanal syndrome
  • rs7023244Benignsingle nucleotide variantOculotrichoanal syndrome
  • rs7025814Benignsingle nucleotide variantOculotrichoanal syndrome
  • rs184394424Conflicting interpretationssingle nucleotide variantTrigonocephaly 2|Irido-corneo-trabecular dysgenesis|Rieger anomaly|Oculotrichoanal syndrome
  • rs281875281Conflicting interpretationssingle nucleotide variantOculotrichoanal syndrome
  • rs41298151Conflicting interpretationssingle nucleotide variantCongenital diaphragmatic hernia|Oculotrichoanal syndrome
  • rs200472299Uncertain significancesingle nucleotide variantOculotrichoanal syndrome
  • rs281875280Uncertain significancesingle nucleotide variantTrigonocephaly 2

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.