Gene entry
FLNC
filamin C
- Chromosome
- 7
- Cytoband
- 7q32.1
- Variants (rsID)
- 30
FLNC is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 7 (region 7q32.1). Its official name is “filamin C”. The reference table lists 30 variants (rsID) for this gene.
Clinically classified variants
25 reference-table entries with clinical significance.
- rs117653869Benignsingle nucleotide variantDilated Cardiomyopathy, Dominant|Myofibrillar myopathy 5|Distal myopathy with posterior leg and anterior hand involvement|Hypertrophic cardiomyopathy 26
- rs146953558Benignsingle nucleotide variantDilated Cardiomyopathy, Dominant|Hypertrophic cardiomyopathy 26|Distal myopathy with posterior leg and anterior hand involvement|Myofibrillar myopathy 5
- rs180834558Benignsingle nucleotide variantHypertrophic cardiomyopathy 26|Distal myopathy with posterior leg and anterior hand involvement|Myofibrillar myopathy 5|Dilated Cardiomyopathy, Dominant
- rs181067717Benignsingle nucleotide variantDilated Cardiomyopathy, Dominant|Myofibrillar myopathy 5|Distal myopathy with posterior leg and anterior hand involvement|Hypertrophic cardiomyopathy 26
- rs192725607Benignsingle nucleotide variantDilated Cardiomyopathy, Dominant|Myofibrillar myopathy 5|Distal myopathy with posterior leg and anterior hand involvement|Hypertrophic cardiomyopathy 26
- rs193159707Benignsingle nucleotide variantDistal myopathy with posterior leg and anterior hand involvement|Myofibrillar myopathy 5|Dilated Cardiomyopathy, Dominant|Hypertrophic cardiomyopathy 26
- rs199652368Benignsingle nucleotide variantDistal myopathy with posterior leg and anterior hand involvement|Hypertrophic cardiomyopathy 26|Dilated Cardiomyopathy, Dominant|Myofibrillar myopathy 5
- rs200215903Benignsingle nucleotide variantMyofibrillar myopathy 5|Distal myopathy with posterior leg and anterior hand involvement|Dilated Cardiomyopathy, Dominant|Hypertrophic cardiomyopathy 26
- rs2291569Benignsingle nucleotide variantDistal myopathy with posterior leg and anterior hand involvement|Dilated Cardiomyopathy, Dominant|Hypertrophic cardiomyopathy 26|Myofibrillar myopathy 5
- rs34373805Benignsingle nucleotide variantDistal myopathy with posterior leg and anterior hand involvement|Dilated Cardiomyopathy, Dominant|Hypertrophic cardiomyopathy 26|Myofibrillar myopathy 5
- rs34972246Benignsingle nucleotide variantDilated Cardiomyopathy, Dominant|Hypertrophic cardiomyopathy 26|Distal myopathy with posterior leg and anterior hand involvement|Myofibrillar myopathy 5
- rs3816885Benignsingle nucleotide variantDistal myopathy with posterior leg and anterior hand involvement|Dilated Cardiomyopathy, Dominant|Hypertrophic cardiomyopathy 26|Myofibrillar myopathy 5
- rs138716837Conflicting interpretationssingle nucleotide variantHypertrophic cardiomyopathy 26|Myofibrillar myopathy 5|Distal myopathy with posterior leg and anterior hand involvement|Dilated Cardiomyopathy, Dominant
- rs148545460Conflicting interpretationssingle nucleotide variantMyofibrillar myopathy 5|Hypertrophic cardiomyopathy 26|Dilated Cardiomyopathy, Dominant|Distal myopathy with posterior leg and anterior hand involvement
- rs149641783Conflicting interpretationssingle nucleotide variantDilated Cardiomyopathy, Dominant|Myofibrillar myopathy 5|Distal myopathy with posterior leg and anterior hand involvement|Hypertrophic cardiomyopathy 26
- rs182845462Conflicting interpretationssingle nucleotide variantDilated Cardiomyopathy, Dominant|Myofibrillar myopathy 5|Hypertrophic cardiomyopathy 26|Distal myopathy with posterior leg and anterior hand involvement
- rs184018403Conflicting interpretationssingle nucleotide variantMyofibrillar myopathy 5|Distal myopathy with posterior leg and anterior hand involvement|Hypertrophic cardiomyopathy 26|Dilated Cardiomyopathy, Dominant
- rs189525930Conflicting interpretationssingle nucleotide variantDilated Cardiomyopathy, Dominant|Myofibrillar myopathy 5|Distal myopathy with posterior leg and anterior hand involvement|Hypertrophic cardiomyopathy 26
- rs387906587Conflicting interpretationssingle nucleotide variantDilated Cardiomyopathy, Dominant|Myofibrillar myopathy 5|Hypertrophic cardiomyopathy 26|Distal myopathy with posterior leg and anterior hand involvement|Myofibrillar myopathy 5|Hypertrophic cardiomyopathy 26|Desmin-related myofibrillar myopathy|Distal myopathy with posterior leg and anterior hand involvement|Distal myopathy with posterior leg and anterior hand involvement
- rs192163925Likely benignsingle nucleotide variantDistal myopathy with posterior leg and anterior hand involvement|Hypertrophic cardiomyopathy 26|Dilated Cardiomyopathy, Dominant|Myofibrillar myopathy 5
- rs118056738Uncertain significancesingle nucleotide variantDilated Cardiomyopathy, Dominant|Myofibrillar myopathy 5|Hypertrophic cardiomyopathy 26|Distal myopathy with posterior leg and anterior hand involvement
- rs138663492Uncertain significancesingle nucleotide variantMyofibrillar myopathy 5|Dilated Cardiomyopathy, Dominant|Hypertrophic cardiomyopathy 26|Distal myopathy with posterior leg and anterior hand involvement
- rs140857707Uncertain significancesingle nucleotide variantMyofibrillar myopathy 5|Distal myopathy with posterior leg and anterior hand involvement|Dilated Cardiomyopathy, Dominant|Hypertrophic cardiomyopathy 26
- rs200928780Uncertain significancesingle nucleotide variantDilated Cardiomyopathy, Dominant|Hypertrophic cardiomyopathy 26|Myofibrillar myopathy 5|Distal myopathy with posterior leg and anterior hand involvement|Hypertrophic cardiomyopathy 26|Myofibrillar myopathy 5|Distal myopathy with posterior leg and anterior hand involvement
- rs200935123Uncertain significancesingle nucleotide variantDistal myopathy with posterior leg and anterior hand involvement|Myofibrillar myopathy 5|Hypertrophic cardiomyopathy 26|Dilated Cardiomyopathy, Dominant
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.