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Gene entry

F8

coagulation factor VIII

Chromosome
X
Cytoband
Xq28
Variants (rsID)
72

F8 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome X (region Xq28). Its official name is “coagulation factor VIII”. The reference table lists 72 variants (rsID) for this gene.

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Clinically classified variants

36 reference-table entries with clinical significance.

  • rs149853218Benignsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs1800291Benignsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs1800292Benignsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs1800297Benignsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs35383156Benignsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs7058826Benignsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs28933673Conflicting interpretationssingle nucleotide variantHereditary factor VIII deficiency disease|Thrombophilia 13, X-linked, due to factor VIII defect
  • rs782198570Conflicting interpretationssingle nucleotide variantHereditary factor VIII deficiency disease|See cases
  • rs782654096Conflicting interpretationssingle nucleotide variantHereditary factor VIII deficiency disease
  • rs200316756Likely benignsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs78373805Likely benignsingle nucleotide variant
  • rs151202877Likely pathogenicsingle nucleotide variantAbnormal bleeding
  • rs111033616Pathogenicsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs137852355Pathogenicsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs137852366Pathogenicsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs137852374Pathogenicsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs137852378Pathogenicsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs137852382Pathogenicsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs137852383Pathogenicsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs137852396Pathogenicsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs137852402Pathogenicsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs137852403Pathogenicsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs137852428Pathogenicsingle nucleotide variantHereditary factor VIII deficiency disease|Hereditary factor IX deficiency disease|Thrombophilia 13, X-linked, due to factor VIII defect
  • rs137852439Pathogenicsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs137852459Pathogenicsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs137852464Pathogenicsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs137852468Pathogenicsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs139526001Pathogenicsingle nucleotide variantHereditary factor IX deficiency disease
  • rs2228152Pathogenicsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs28933668Pathogenicsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs28933680Pathogenicsingle nucleotide variantHereditary factor VIII deficiency disease
  • rs28935499Pathogenicsingle nucleotide variantFACTOR VIII (OKAYAMA)|Hereditary factor VIII deficiency disease|Hereditary factor IX deficiency disease
  • rs387906445PathogenicDuplicationHereditary factor VIII deficiency disease
  • rs387906452PathogenicDeletionHereditary factor VIII deficiency disease
  • rs397514036PathogenicDuplicationHereditary factor VIII deficiency disease
  • rs1800294Uncertain significancesingle nucleotide variantHereditary factor VIII deficiency disease

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.