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Gene entry

F5

coagulation factor V

Chromosome
1
Cytoband
1q24.2
Variants (rsID)
46

F5 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 1 (region 1q24.2). Its official name is “coagulation factor V”. The reference table lists 46 variants (rsID) for this gene.

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Clinically classified variants

20 reference-table entries with clinical significance.

  • rs13306334Benignsingle nucleotide variantThrombophilia due to activated protein C resistance|Budd-Chiari syndrome|Factor V deficiency|Thrombophilia due to thrombin defect
  • rs6018Benignsingle nucleotide variantThrombophilia due to thrombin defect|Thrombophilia due to activated protein C resistance|Factor V deficiency|Budd-Chiari syndrome
  • rs6020Benignsingle nucleotide variantThrombophilia due to activated protein C resistance|Thrombophilia due to thrombin defect|Factor V deficiency|Budd-Chiari syndrome
  • rs6026Benignsingle nucleotide variantThrombophilia due to activated protein C resistance|Thrombophilia due to thrombin defect|Budd-Chiari syndrome|Factor V deficiency
  • rs6027Benignsingle nucleotide variantThrombophilia due to activated protein C resistance
  • rs6028Benignsingle nucleotide variantThrombophilia due to thrombin defect|Thrombophilia due to activated protein C resistance|Factor V deficiency|Budd-Chiari syndrome
  • rs6032Benignsingle nucleotide variantBudd-Chiari syndrome|Factor V deficiency|Thrombophilia due to activated protein C resistance|Thrombophilia due to thrombin defect
  • rs6427196Benignsingle nucleotide variantBudd-Chiari syndrome|Factor V deficiency|Thrombophilia due to activated protein C resistance|Thrombophilia due to thrombin defect
  • rs9332485Benignsingle nucleotide variantFactor V deficiency|Thrombophilia due to thrombin defect|Thrombophilia due to activated protein C resistance|Budd-Chiari syndrome
  • rs9332608Benignsingle nucleotide variantThrombophilia due to activated protein C resistance|Factor V deficiency|Thrombophilia due to thrombin defect|Budd-Chiari syndrome
  • rs9332701Benignsingle nucleotide variantThrombophilia due to activated protein C resistance|Budd-Chiari syndrome|Thrombophilia due to thrombin defect|Factor V deficiency
  • rs144979314Conflicting interpretationssingle nucleotide variantThrombophilia due to activated protein C resistance|Budd-Chiari syndrome|Thrombophilia due to thrombin defect|Factor V deficiency
  • rs182566496Conflicting interpretationssingle nucleotide variantThrombophilia due to activated protein C resistance|Budd-Chiari syndrome|Thrombophilia due to thrombin defect|Factor V deficiency
  • rs201078171Conflicting interpretationssingle nucleotide variantThrombophilia due to activated protein C resistance|Budd-Chiari syndrome|Factor V deficiency|Thrombophilia due to thrombin defect
  • rs201510575Conflicting interpretationssingle nucleotide variantThrombophilia due to activated protein C resistance|Budd-Chiari syndrome|Factor V deficiency|Thrombophilia due to thrombin defect
  • rs4524Conflicting interpretationssingle nucleotide variantThrombophilia due to activated protein C resistance
  • rs6030Conflicting interpretationssingle nucleotide variantThrombophilia due to activated protein C resistance
  • rs118203910Likely pathogenicsingle nucleotide variantFactor V deficiency
  • rs118203907Pathogenicsingle nucleotide variantFactor V deficiency
  • rs6025Pathogenicsingle nucleotide variantBudd-Chiari syndrome, susceptibility to|Ischemic stroke|Pregnancy loss, recurrent, susceptibility to, 1|Factor V deficiency|Thrombophilia due to activated protein C resistance|Factor V deficiency|Thrombophilia due to activated protein C resistance|Susceptibility to severe coronavirus disease (COVID-19) due to an impaired coagulation process

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.