Genetics University — Research, Education, Medical Genetics
Knowledge Hub

Gene entry

F11

coagulation factor XI

Chromosome
4
Cytoband
4q35.2
Variants (rsID)
30

F11 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 4 (region 4q35.2). Its official name is “coagulation factor XI”. The reference table lists 30 variants (rsID) for this gene.

ShareE-MailWhatsAppLinkedInXFacebookTelegram

Clinically classified variants

14 reference-table entries with clinical significance.

  • rs4253429Benignsingle nucleotide variantHereditary factor XI deficiency disease
  • rs4253865Benignsingle nucleotide variantHereditary factor XI deficiency disease
  • rs5974Benignsingle nucleotide variantHereditary factor XI deficiency disease|Plasma factor XI deficiency
  • rs121965070Conflicting interpretationssingle nucleotide variantHereditary factor XI deficiency disease
  • rs756908183Conflicting interpretationssingle nucleotide variantHereditary factor XI deficiency disease|Abnormal bleeding|Plasma factor XI deficiency
  • rs121965071Likely pathogenicsingle nucleotide variantHereditary factor XI deficiency disease
  • rs281875250Likely pathogenicsingle nucleotide variantHereditary factor XI deficiency disease
  • rs28934608Likely pathogenicsingle nucleotide variantHereditary factor XI deficiency disease
  • rs121965063Pathogenicsingle nucleotide variantHereditary factor XI deficiency disease|Thrombocytopenia|Abnormal bleeding|Inborn genetic diseases|Plasma factor XI deficiency
  • rs121965064Pathogenicsingle nucleotide variantHereditary factor XI deficiency disease|Plasma factor XI deficiency|Factor XI
  • rs121965065Pathogenicsingle nucleotide variantHereditary factor XI deficiency disease
  • rs121965069Pathogenicsingle nucleotide variantHereditary factor XI deficiency disease|Plasma factor XI deficiency
  • rs200593979Uncertain significancesingle nucleotide variantHereditary factor XI deficiency disease
  • rs200622588Uncertain significancesingle nucleotide variantHereditary factor XI deficiency disease

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.