Gene entry
DYRK1A
dual specificity tyrosine phosphorylation regulated kinase 1A
- Chromosome
- 21
- Cytoband
- 21q22.13
- Variants (rsID)
- 23
DYRK1A is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 21 (region 21q22.13). Its official name is “dual specificity tyrosine phosphorylation regulated kinase 1A”. The reference table lists 23 variants (rsID) for this gene.
Clinically classified variants
4 reference-table entries with clinical significance.
- rs145857775Benignsingle nucleotide variantDYRK1A-related intellectual disability syndrome|History of neurodevelopmental disorder
- rs147650865Likely benignsingle nucleotide variantHistory of neurodevelopmental disorder|DYRK1A-related intellectual disability syndrome
- rs797045041Pathogenicsingle nucleotide variantDYRK1A-related intellectual disability syndrome|Complex neurodevelopmental disorder|Intellectual disability
- rs869312708Pathogenicsingle nucleotide variantDYRK1A-related intellectual disability syndrome
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.