Genetics University — Research, Education, Medical Genetics
Knowledge Hub

Gene entry

DOCK8

dedicator of cytokinesis 8

Chromosome
9
Cytoband
9p24.3
Variants (rsID)
119

DOCK8 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 9 (region 9p24.3). Its official name is “dedicator of cytokinesis 8”. The reference table lists 119 variants (rsID) for this gene.

ShareE-MailWhatsAppLinkedInXFacebookTelegram

Clinically classified variants

18 reference-table entries with clinical significance.

  • rs11789099Benignsingle nucleotide variantCombined immunodeficiency due to DOCK8 deficiency
  • rs145573166Benignsingle nucleotide variantCombined immunodeficiency due to DOCK8 deficiency
  • rs16937932Benignsingle nucleotide variantCombined immunodeficiency due to DOCK8 deficiency
  • rs17673268Benignsingle nucleotide variantCombined immunodeficiency due to DOCK8 deficiency
  • rs184867151Benignsingle nucleotide variantCombined immunodeficiency due to DOCK8 deficiency
  • rs3209441Benignsingle nucleotide variantCombined immunodeficiency due to DOCK8 deficiency
  • rs34098809Benignsingle nucleotide variantCombined immunodeficiency due to DOCK8 deficiency
  • rs3780338Benignsingle nucleotide variantCombined immunodeficiency due to DOCK8 deficiency
  • rs75411647Benignsingle nucleotide variantCombined immunodeficiency due to DOCK8 deficiency
  • rs116920018Conflicting interpretationssingle nucleotide variantCombined immunodeficiency due to DOCK8 deficiency
  • rs151094543Conflicting interpretationssingle nucleotide variantCombined immunodeficiency due to DOCK8 deficiency
  • rs192864327Conflicting interpretationssingle nucleotide variantCombined immunodeficiency due to DOCK8 deficiency|Intellectual disability|Severe combined immunodeficiency disease
  • rs34390308Conflicting interpretationssingle nucleotide variantCombined immunodeficiency due to DOCK8 deficiency
  • rs753242273Conflicting interpretationssingle nucleotide variantCombined immunodeficiency due to DOCK8 deficiency
  • rs75352090Conflicting interpretationssingle nucleotide variantInborn genetic diseases|Combined immunodeficiency due to DOCK8 deficiency
  • rs140148619Uncertain significancesingle nucleotide variantCombined immunodeficiency due to DOCK8 deficiency
  • rs145844320Uncertain significancesingle nucleotide variantCombined immunodeficiency due to DOCK8 deficiency
  • rs147287319Uncertain significancesingle nucleotide variantCombined immunodeficiency due to DOCK8 deficiency|Intellectual disability

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.