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Gene entry

DICER1

dicer 1, ribonuclease III

Chromosome
14
Cytoband
14q32.13
Variants (rsID)
36

DICER1 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 14 (region 14q32.13). Its official name is “dicer 1, ribonuclease III”. The reference table lists 36 variants (rsID) for this gene.

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Clinically classified variants

26 reference-table entries with clinical significance.

  • rs147493562Benignsingle nucleotide variantDICER1 syndrome|Hereditary cancer-predisposing syndrome
  • rs1778057Benignsingle nucleotide variantDICER1 syndrome|Goiter, multinodular 1, with or without Sertoli-Leydig cell tumors
  • rs141163928Conflicting interpretationssingle nucleotide variantHereditary cancer-predisposing syndrome|DICER1 syndrome|Malignant tumor of breast
  • rs146584765Conflicting interpretationssingle nucleotide variantDICER1 syndrome|Hereditary cancer-predisposing syndrome
  • rs148758903Conflicting interpretationssingle nucleotide variantDICER1 syndrome|Hereditary cancer-predisposing syndrome|Goiter, multinodular 1, with or without Sertoli-Leydig cell tumors
  • rs181018393Conflicting interpretationssingle nucleotide variantDICER1 syndrome|Hereditary cancer-predisposing syndrome
  • rs189119295Conflicting interpretationssingle nucleotide variantDICER1 syndrome|Hereditary cancer-predisposing syndrome
  • rs587778229Conflicting interpretationssingle nucleotide variantDICER1 syndrome|Hereditary cancer-predisposing syndrome
  • rs770904411Conflicting interpretationsDeletionPleuropulmonary blastoma|DICER1 syndrome|Hereditary cancer-predisposing syndrome
  • rs869025262Conflicting interpretationssingle nucleotide variantAnophthalmia-microphthalmia syndrome|DICER1 syndrome|Hereditary cancer-predisposing syndrome
  • rs878855246Conflicting interpretationssingle nucleotide variantDICER1 syndrome|Hereditary cancer-predisposing syndrome|Rhabdomyosarcoma|Pleuropulmonary blastoma
  • rs137852976Likely pathogenicsingle nucleotide variantPleuropulmonary blastoma|DICER1 syndrome
  • rs137852977Pathogenicsingle nucleotide variantPleuropulmonary blastoma|DICER1 syndrome|Hereditary cancer-predisposing syndrome
  • rs137852978Pathogenicsingle nucleotide variantPleuropulmonary blastoma|DICER1 syndrome|Hereditary cancer-predisposing syndrome
  • rs137852979Pathogenicsingle nucleotide variantPleuropulmonary blastoma|DICER1 syndrome
  • rs864622626Pathogenicsingle nucleotide variantDICER1 syndrome
  • rs875989779Pathogenicsingle nucleotide variantPineoblastoma|DICER1 syndrome
  • rs878855274PathogenicDeletionDICER1 syndrome
  • rs886037672Pathogenicsingle nucleotide variantDICER1 syndrome|Hereditary cancer-predisposing syndrome
  • rs886037680PathogenicDeletionDICER1 syndrome|Hereditary cancer-predisposing syndrome
  • rs886037684Pathogenicsingle nucleotide variantDICER1 syndrome|Hereditary cancer-predisposing syndrome
  • rs886037689Pathogenicsingle nucleotide variantDICER1 syndrome|Hereditary cancer-predisposing syndrome
  • rs886037691Pathogenicsingle nucleotide variantDICER1 syndrome
  • rs886037723Pathogenicsingle nucleotide variantDICER1 syndrome|Hereditary cancer-predisposing syndrome
  • rs200890670Uncertain significancesingle nucleotide variantDICER1 syndrome|Hereditary cancer-predisposing syndrome
  • rs201523588Uncertain significancesingle nucleotide variantDICER1 syndrome|Hereditary cancer-predisposing syndrome

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.