Gene entry
CYP2D6
cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene)
- Chromosome
- 22
- Cytoband
- 22q13.2
- Variants (rsID)
- 121
CYP2D6 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 22 (region 22q13.2). Its official name is “cytochrome P450 family 2 subfamily D member 6 (gene/pseudogene)”. The reference table lists 121 variants (rsID) for this gene.
Clinically classified variants
7 reference-table entries with clinical significance.
- rs730882170Drug responseDeletion
- rs1135824Likely benignsingle nucleotide variant
- rs28371717Likely benignsingle nucleotide variantTramadol response
- rs28371725Likely benignsingle nucleotide variantTramadol response|Deutetrabenazine response|Tamoxifen response
- rs5030655Likely benignDeletionDebrisoquine, poor metabolism of|Deutetrabenazine response|Tamoxifen response
- rs5030865Likely benignsingle nucleotide variantDebrisoquine, poor metabolism of
- rs5030867Likely benignsingle nucleotide variant
Other listed variants
- rs1058172
- rs1080990
- rs1080993
- rs1135829
- rs1135832
- rs1135833
- rs1135835
- rs1135838
- rs1135839
- rs28371729
- rs28371732
- rs28371733
- rs28371735
- rs28371736
- rs35046171
- rs58188898
- rs59360719
- rs67497403
- rs72549346
- rs72549348
- rs72549349
- rs72549353
- rs72549354
- rs72549358
- rs74802369
- rs74962936
- rs76187628
- rs76210340
- rs78209835
- rs78459009
- rs78482768
- rs79292917
- rs79392742
- rs115213325
- rs138100349
- rs138417770
- rs140513104
- rs142302759
- rs146540061
- rs146838345
- rs147943410
- rs148241836
- rs148250267
- rs148382141
- rs148769737
- rs149686350
- rs150445731
- rs180847475
- rs186133763
- rs188062577
- rs199722016
- rs199849357
- rs201297021
- rs201377835
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.