Gene entry
CYP2C19
cytochrome P450 family 2 subfamily C member 19
- Chromosome
- 10
- Cytoband
- 10q23.33
- Variants (rsID)
- 66
CYP2C19 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 10 (region 10q23.33). Its official name is “cytochrome P450 family 2 subfamily C member 19”. The reference table lists 66 variants (rsID) for this gene.
Clinically classified variants
20 reference-table entries with clinical significance.
- rs118203756Drug responsesingle nucleotide variantCYP2C19: uncertain function
- rs118203759Drug responsesingle nucleotide variantCYP2C19: decreased function
- rs12248560Drug responsesingle nucleotide variantCYP2C19: increased function
- rs12769205Drug responsesingle nucleotide variantCYP2C19: no function
- rs1288601658Drug responsesingle nucleotide variantCYP2C19: uncertain function
- rs138142612Drug responsesingle nucleotide variantCYP2C19: normal function
- rs140278421Drug responsesingle nucleotide variantCYP2C19: no function
- rs145328984Drug responsesingle nucleotide variantCYP2C19: uncertain function
- rs17879685Drug responsesingle nucleotide variantCYP2C19: normal function
- rs375781227Drug responsesingle nucleotide variantCYP2C19: decreased function
- rs41291556Drug responsesingle nucleotide variantCYP2C19: no function
- rs4986893Drug responsesingle nucleotide variantMephenytoin, poor metabolism of|Proguanil, poor metabolism of|CYP2C19: no function|Acute coronary syndrome
- rs55640102Drug responsesingle nucleotide variantCYP2C19: uncertain function
- rs56337013Drug responsesingle nucleotide variantMephenytoin, poor metabolism of|CYP2C19: no function
- rs72552267Drug responsesingle nucleotide variantCYP2C19: no function
- rs72558186Drug responsesingle nucleotide variantCYP2C19: no function
- rs7902257Drug responsesingle nucleotide variantCYP2C19: uncertain function
- rs111490789Othersingle nucleotide variant
- rs113164681Othersingle nucleotide variant
- rs118203757Othersingle nucleotide variant
Other listed variants
- rs4388808
- rs4417205
- rs4494250
- rs4917612
- rs4917623
- rs4986894
- rs7916649
- rs11188092
- rs11528090
- rs11592737
- rs12268020
- rs12571421
- rs12768009
- rs17878459
- rs17878649
- rs17884832
- rs17885179
- rs17886522
- rs28399505
- rs28399513
- rs28399514
- rs59162501
- rs72558185
- rs75105257
- rs116992754
- rs140554854
- rs141417293
- rs143612134
- rs144036596
- rs144056033
- rs145119820
- rs150790215
- rs185136199
- rs190777341
- rs200003088
- rs200936950
- rs201132803
- rs375283723
- rs527499296
- rs539248491
- rs545642100
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.