Gene entry
CYP2B6
cytochrome P450 family 2 subfamily B member 6
- Chromosome
- 19
- Cytoband
- 19q13.2
- Variants (rsID)
- 85
CYP2B6 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 19 (region 19q13.2). Its official name is “cytochrome P450 family 2 subfamily B member 6”. The reference table lists 85 variants (rsID) for this gene.
Clinically classified variants
6 reference-table entries with clinical significance.
- rs186335453Drug responsesingle nucleotide variantEfavirenz response
- rs28399499Drug responsesingle nucleotide variantnevirapine response - Toxicity
- rs36079186Drug responsesingle nucleotide variantEfavirenz response
- rs373489637Drug responsesingle nucleotide variantEfavirenz response
- rs3745274Drug responsesingle nucleotide variantEfavirenz response|efavirenz response - Metabolism/PK|efavirenz response - Toxicity|nevirapine response - Metabolism/PK
- rs8192719Not classifiedintron_variantIschemia|Efavirenz, Poor Metabolism of
Other listed variants
- rs707265
- rs1042389
- rs1962261
- rs2054675
- rs2099361
- rs2279341
- rs2279342
- rs2279344
- rs2279345
- rs3760657
- rs3786547
- rs4802100
- rs4803417
- rs4803418
- rs4803419
- rs6508964
- rs7246465
- rs7260329
- rs8101756
- rs8192709
- rs8192718
- rs12721646
- rs12721649
- rs12721652
- rs12721655
- rs12721656
- rs28399491
- rs34223104
- rs34646544
- rs34698757
- rs34826503
- rs35010098
- rs35266616
- rs35449271
- rs35468935
- rs35622401
- rs36056539
- rs36060847
- rs36118214
- rs45466193
- rs45482602
- rs71337576
- rs79472458
- rs111688353
- rs114957222
- rs116960502
- rs117323987
- rs117398851
- rs138264188
- rs138652715
- rs139029625
- rs139512553
- rs145884402
- rs149403002
- rs180791497
- rs181586398
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.