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Gene entry

CYBB

cytochrome b-245 beta chain

Chromosome
X
Cytoband
Xp21.1-p11.4
Variants (rsID)
27

CYBB is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome X (region Xp21.1-p11.4). Its official name is “cytochrome b-245 beta chain”. The reference table lists 27 variants (rsID) for this gene.

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Clinically classified variants

18 reference-table entries with clinical significance.

  • rs139670417Benignsingle nucleotide variantGranulomatous disease, chronic, X-linked|Chronic granulomatous disease
  • rs137854594Likely pathogenicsingle nucleotide variantGranulomatous disease, chronic, X-linked, variant|Granulomatous disease, chronic, X-linked
  • rs151344482Likely pathogenicsingle nucleotide variant
  • rs193922445Likely pathogenicDuplicationGranulomatous disease, chronic, X-linked
  • rs193922446Likely pathogenicDeletionGranulomatous disease, chronic, X-linked
  • rs137854587Pathogenicsingle nucleotide variantGranulomatous disease, chronic, X-linked
  • rs137854588Pathogenicsingle nucleotide variantGranulomatous disease, chronic, X-linked
  • rs137854590Pathogenicsingle nucleotide variantGranulomatous disease, chronic, X-linked, variant
  • rs137854591Pathogenicsingle nucleotide variantGranulomatous disease, chronic, X-linked, variant|Granulomatous disease, chronic, X-linked
  • rs137854592Pathogenicsingle nucleotide variantGranulomatous disease, chronic, X-linked|Chronic granulomatous disease
  • rs137854593Pathogenicsingle nucleotide variantGranulomatous disease, chronic, X-linked
  • rs137854595Pathogenicsingle nucleotide variantGranulomatous disease, chronic, X-linked, variant
  • rs151344454Pathogenicsingle nucleotide variantGranulomatous disease, chronic, X-linked
  • rs151344474Pathogenicsingle nucleotide variant
  • rs151344481Pathogenicsingle nucleotide variantGranulomatous disease, chronic, X-linked
  • rs193922448Pathogenicsingle nucleotide variantGranulomatous disease, chronic, X-linked
  • rs193922449Pathogenicsingle nucleotide variantGranulomatous disease, chronic, X-linked
  • rs387906485Pathogenicsingle nucleotide variantGranulomatous disease, chronic, X-linked

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.