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Gene entry

CFI

complement factor I

Chromosome
4
Cytoband
4q25
Variants (rsID)
26

CFI is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 4 (region 4q25). Its official name is “complement factor I”. The reference table lists 26 variants (rsID) for this gene.

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Clinically classified variants

5 reference-table entries with clinical significance.

  • rs113612355Benignsingle nucleotide variantAtypical hemolytic-uremic syndrome with I factor anomaly
  • rs61733901Conflicting interpretationssingle nucleotide variantAtypical hemolytic-uremic syndrome with I factor anomaly
  • rs112534524Likely benignsingle nucleotide variantAtypical hemolytic-uremic syndrome with I factor anomaly|Chronic kidney disease
  • rs121964912Pathogenicsingle nucleotide variantFactor I deficiency
  • rs121964918Risk factorsingle nucleotide variantAtypical hemolytic-uremic syndrome with I factor anomaly

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.