Genetics University — Research, Education, Medical Genetics
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Gene entry

CFB

complement factor B

Chromosome
6
Cytoband
6p21.33
Variants (rsID)
24

CFB is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 6 (region 6p21.33). Its official name is “complement factor B”. The reference table lists 24 variants (rsID) for this gene.

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Clinically classified variants

4 reference-table entries with clinical significance.

  • rs4151659Benignsingle nucleotide variantAtypical hemolytic-uremic syndrome with B factor anomaly|Macular degeneration
  • rs4151672Benignsingle nucleotide variantMacular degeneration|Atypical hemolytic-uremic syndrome with B factor anomaly
  • rs45484591Benignsingle nucleotide variantMacular degeneration|Complement factor b deficiency|Atypical hemolytic-uremic syndrome with B factor anomaly|Complement component 2 deficiency
  • rs201798809Conflicting interpretationssingle nucleotide variantMacular degeneration|Atypical hemolytic-uremic syndrome with B factor anomaly

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.