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Gene entry

C2

complement C2

Chromosome
6
Cytoband
6p21.33
Variants (rsID)
42

C2 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 6 (region 6p21.33). Its official name is “complement C2”. The reference table lists 42 variants (rsID) for this gene.

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Clinically classified variants

12 reference-table entries with clinical significance.

  • rs1048709Benignsingle nucleotide variantComplement component 2 deficiency|Atypical hemolytic-uremic syndrome with B factor anomaly|Macular degeneration|Complement factor b deficiency
  • rs12614Benignsingle nucleotide variantFactor B fast/slow polymorphism|Atypical hemolytic-uremic syndrome|Macular degeneration|Complement component 2 deficiency|Atypical hemolytic-uremic syndrome with B factor anomaly
  • rs2072634Benignsingle nucleotide variantAtypical hemolytic-uremic syndrome with B factor anomaly|Macular degeneration|Complement component 2 deficiency
  • rs36221133Benignsingle nucleotide variantMacular degeneration|Complement component 2 deficiency|Atypical hemolytic-uremic syndrome|Age related macular degeneration 14
  • rs4151651Benignsingle nucleotide variantComplement component 2 deficiency|Macular degeneration|Atypical hemolytic-uremic syndrome with B factor anomaly
  • rs4151667Benignsingle nucleotide variantAge related macular degeneration 14|Macular degeneration|Complement component 2 deficiency|Atypical hemolytic-uremic syndrome|Atypical hemolytic-uremic syndrome with B factor anomaly
  • rs4151669Benignsingle nucleotide variantMacular degeneration|Complement component 2 deficiency|Atypical hemolytic-uremic syndrome with B factor anomaly
  • rs45600936Benignsingle nucleotide variantMacular degeneration|Complement component 2 deficiency|Atypical hemolytic-uremic syndrome|Atypical hemolytic-uremic syndrome with B factor anomaly
  • rs9332739Benignsingle nucleotide variantAge related macular degeneration 14|Complement component 2 deficiency
  • rs140225293Conflicting interpretationssingle nucleotide variantAtypical hemolytic-uremic syndrome|Macular degeneration|C2-related disorders
  • rs142243595Conflicting interpretationssingle nucleotide variantAtypical hemolytic-uremic syndrome|Complement component 2 deficiency|Macular degeneration|Age related macular degeneration 14
  • rs547154Protectivesingle nucleotide variantAge related macular degeneration 14

Other listed variants

Public references

Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.