Gene entry
APOL1
apolipoprotein L1
- Chromosome
- 22
- Cytoband
- 22q12.3
- Variants (rsID)
- 20
APOL1 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 22 (region 22q12.3). Its official name is “apolipoprotein L1”. The reference table lists 20 variants (rsID) for this gene.
Clinically classified variants
7 reference-table entries with clinical significance.
- rs136177Benignsingle nucleotide variant
- rs60910145Benignsingle nucleotide variantHyalinosis, Segmental Glomerular|Glomerulonephritis|Proteinuria|Focal segmental glomerulosclerosis|Steroid-resistant nephrotic syndrome|Focal segmental glomerulosclerosis|Focal segmental glomerulosclerosis|Sickled erythrocytes|Nephrotic range proteinuria
- rs73885319Conflicting interpretationssingle nucleotide variantHyalinosis, Segmental Glomerular|Steroid-resistant nephrotic syndrome|Focal segmental glomerulosclerosis|Glomerulonephritis|Sickled erythrocytes|Focal segmental glomerulosclerosis|Nephrotic range proteinuria|Proteinuria|Focal segmental glomerulosclerosis
- rs136174Not classifiedsynonymous_variant
- rs136175Not classifiedmissense_variant
- rs136176Not classifiedmissense_variant
- rs2239785Not classifiedmissense_variant
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.