Gene entry
APOE
apolipoprotein E
- Chromosome
- 19
- Cytoband
- 19q13.32
- Variants (rsID)
- 14
APOE is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 19 (region 19q13.32). Its official name is “apolipoprotein E”. The reference table lists 14 variants (rsID) for this gene.
Clinically classified variants
12 reference-table entries with clinical significance.
- rs199768005Benignsingle nucleotide variant
- rs769452Conflicting interpretationssingle nucleotide variantAlzheimer disease 4
- rs769455Conflicting interpretationssingle nucleotide variantFamilial type 3 hyperlipoproteinemia
- rs439401Drug responsesingle nucleotide variantWarfarin response
- rs7412Drug responsesingle nucleotide variantFamilial type 3 hyperlipoproteinemia|atorvastatin response - Efficacy|Warfarin response|Hypercholesterolemia
- rs201672011Likely benignsingle nucleotide variantAPOE5 VARIANT
- rs140808909Othersingle nucleotide variant
- rs190853081Othersingle nucleotide variantCerebral Palsy
- rs28931577Othersingle nucleotide variant
- rs405509Risk factorsingle nucleotide variantCoronary artery disease, severe, susceptibility to
- rs267606661Uncertain significancesingle nucleotide variant
- rs267606664Uncertain significancesingle nucleotide variantHypercholesterolemia
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.