Gene entry
APEX1
apurinic/apyrimidinic endodeoxyribonuclease 1
- Chromosome
- 14
- Cytoband
- 14q11.2
- Variants (rsID)
- 4
APEX1 is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 14 (region 14q11.2). Its official name is “apurinic/apyrimidinic endodeoxyribonuclease 1”. The reference table lists 4 variants (rsID) for this gene.
Clinically classified variants
1 reference-table entries with clinical significance.
- rs1130409Not classifiedmissense_variantProstate Cancer|Renal Cell Carcinoma, Nonpapillary|Ataxia, Combined Cerebellar and Peripheral, with Hearing Loss and Diabetes Mellitus|Hearing Loss, Noise-Induced|Lung Cancer|Breast Cancer|Ovarian Cancer|Posterior Uveitis|Hypertension, Essential|Choroiditis|Uveitis|Lung Cancer Susceptibility 1|Toxoplasmosis|Neuroblastoma|Ocular Toxoplasmosis|Diffuse Large B-Cell Lymphoma|Squamous Cell Carcinoma|Cerebral Cavernous Malformations
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.