Gene entry
ALOX12B
arachidonate 12-lipoxygenase, 12R type
- Chromosome
- 17
- Cytoband
- 17p13.1
- Variants (rsID)
- 11
ALOX12B is a protein-coding gene, meaning the body reads it as instructions to build a protein, located on chromosome 17 (region 17p13.1). Its official name is “arachidonate 12-lipoxygenase, 12R type”. The reference table lists 11 variants (rsID) for this gene.
Clinically classified variants
6 reference-table entries with clinical significance.
- rs72842957Benignsingle nucleotide variantAutosomal recessive congenital ichthyosis 2
- rs397514532Conflicting interpretationssingle nucleotide variantAutosomal recessive congenital ichthyosis 2|Congenital ichthyosiform erythroderma|Congenital nonbullous ichthyosiform erythroderma
- rs137853024Pathogenicsingle nucleotide variantAutosomal recessive congenital ichthyosis 2
- rs199545653Pathogenicsingle nucleotide variantAutosomal recessive congenital ichthyosis 2
- rs199766569Pathogenicsingle nucleotide variantAutosomal recessive congenital ichthyosis 2|Ichthyosis|Lamellar ichthyosis
- rs397514527Pathogenicsingle nucleotide variantAutosomal recessive congenital ichthyosis 2
Other listed variants
Public references
Data from the institutional reference table and public NCBI annotation. For education only; not a substitute for medical or genetic counselling.